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What FOXO4-DRI Does NOT Do Based on current evidence, FOXO4-DRI does not: Replace exercise or nutrition Senescent cell clearance does not substitute for the hundreds of other mechanisms through which healthy habits protect against aging Kill cancer cells directly While some research explores FOXO4-DRI in cancer contexts, it is not an anti-cancer therapy

*Correspondence: Niels Bovenschen, [email protected] This article was submitted to Molecular and Cellular Oncology, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Br J Clin Pharmacol 2012;73(5):750-7

The release also addresses supplier evaluation considerations for research-use-only compounds